DAY 2

Friday. Sept 23, 2022

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DAY 2

8:30 am - 9:00 am

SESSION III

Short Talks – Selected from Abstract

Chairs: Wen Shen, PhD

Sponsored by 

  8:30 am – 8:45 am

Lorea Iturri, PhD
Novel approaches in radiotherapy in a rat glioblastoma model: immune responses generated by MBRT and proton FLASH therapy
Institut Curie, Paris France

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8:45 am – 9:00 am

Irma Telarovic, MD
Delayed tumor draining lymph node irradiation to maximize the treatment benefit of radiotherapy-immunotherapy combination
University of Zurich, Zurich, Switzeland

9:00 am - 10:30 am

SESSION IV

Combinations of Radiotherapy and Immunotherapy:
From Preclinical Models to Clinical Translation

Chairs: Claire Vanpouille-Box, PhD and John Ng, MD

9:00 am – 9:30 am

Kevin Harrington, PhD
Driving T- and NK-cell-based anti-tumour immunity by combining radiation and DNA damage response inhibition
The Institute of Cancer Research, London, UK          

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9:30 am – 10:00 am

Fernanda Herrera, MD, PhD
Low dose irradiation for tumor immune reprogramming
Université de Lausanne, Lausanne, Switzerland

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10:00 am – 10:30 am

Theodore S. Hong, MD
PD-1/CTLA4 inhibition with radiation in MSS colorectal and pancreatic cancer
Massachusetts General Hospital, Boston, MA, USA

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Coffee Break 10:30 am - 11:00 am

11:00 am - 12:30 pm

SESSION V

Local and Systemic Modulators of Immunity

Chairs: Alan Melcher, MD, PhD and Inês Mota, PhD

11:00 am - 11:30 am

Weiping Zou, MD, PhD
Macrophages in cancer metastasis and immunity
University of Michigan, Ann Harbor, MI, USA        

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11:30 am – 12:00 pm

Stephen L. Shiao, MD, PhD
Microbiome regulation of anti-tumor immunity elicited by radiation and immunotherapy
Cedars-Sinai Medical Center, Los Angeles, CA, USA

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12:00 pm – 12:30 pm

Sean Pitroda, MD
Concurrent radiation and immune checkpoint blockade enhances local tumor immunity and improves survival in highly aneuploid non-small cell lung cancer
University of Chicago, Chicago, IL, USA

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Lunch break 12:30 pm - 2:00 pm

2:00 pm - 3:30 pm

SESSION VI

Radiotherapy and Immunotherapy Combinations to Manage Metastatic Disease

Chairs: Eric Deutsch, MD, PhD and Maud Charpentier, PhD

Sponsored by 

2:00 pm – 2:30 pm

Robert D. Timmerman, MD
PULSAR: The adaptation of SABR toward personalized medicine
UT Southwestern University, Dallas, TX, USA

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2:30 pm – 3:00 pm

David C. Lyden, PhD
Extracellular vesicles and particles promote organotropic metastasis and systemic disease
Weill Cornell Medical College, New York, NY, USA

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3:00 pm – 3:30 pm

Ralph Weichselbaum MD, PhD
Radiotherapy and Immunotherapy: The hype and the hope
University of Chicago, Chicago, IL, USA

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Coffee Break 3:30 pm - 4:00 pm

4:00 pm - 5:30 pm

SESSION VII

Imaging Immune Responses in the Irradiated Tumor Microenvironment

Chairs: Lorenzo Galluzzi, PhD and Zohaib Khan, PhD

4:00 pm – 4:30 pm

Eric Deutsch, MD, PhD
Personalization of immuno-radiotherapy with imaging: the next game changer?
Gustave Roussy Cancer Center, Paris, France       

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4:30 pm – 5:00 pm

Simon Knott, PhD
Single cell profiling of the response to pembrolizumab and radiation therapy in human breast tumors:
Triple Negative Breast Cancers React to Pembrolizumab & Radiation Therapy with Three Distinct Immune Response Trajectories
Cedars-Sinai Medical Center, Los Angeles, CA, USA

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5:00 pm – 5:30 pm

Chris Xu, PhD
Intravital 3-photon imaging of entire mouse lymph nodes
Cornell University, Ithaca, New York, USA

6:30 pm - 9:30 pm

ROOFTOP SOCIAL EVENT

(Prior registration required)

Monarch Rooftop

DAY 3

Saturday. Sept 24, 2022

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DAY 3

8:30 am - 9:00 am

SESSION VIII

Short Talks – Selected from Abstracts

Chairs: Michele Mondini, PhD

Sponsored by

8:30 am – 8:45 am

Charleen Chan, MD
Dynamics of T-cell-driven immune responses to radiotherapy and immunotherapy in a HPV16⁺ model of head and neck cancer
The Institute of Cancer Research, London, UK

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8:45 am – 9:00 am

Anna Mondino, PhD
Prostate-confined radiotherapy empowers TCR/CAR T cells against primary and metastatic prostate adenocarcinoma
IRCCS San Raffaele Scientific Institute, Milan, Italy

9:00 am – 10:30 am

SESSION IX

T cell Interactions with the Irradiated Tumor Microenvironment

Chairs: Sheila Spada, PhD and Anna Wilkins, MD, PhD

9:00 am – 9:30 am

Sergio A. Quezada, PhD
Regulatory T Cells as determinants of adaptive and innate function in brain tumours
University College London, London, UK

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9:30 am – 10:00 am

Jamie Honeychurch, PhD
The impact of radiation therapy on lymphocyte killing of cancer cells
University of Manchester, Manchester, UK

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10:00 am – 10:30 am

Monica L. Guzman, PhD
Harnessing RT as a means to improve the therapeutic potential of CAR T cells
Weill Cornell Medical College, New York, NY, USA

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Coffee Break 10:30 am - 11:00 am

11:00 am – 12:00 pm

PANEL

Normal tissue exposure: implications for radscopal effect?
Chairs: Mansoor Ahmed, PhD and Chandan Guha, MBBS, PhD

Sponsored by 

11:00 am – 11:20 am

James W. Welsh, MD
The Univesity of Texas MD Anderson Cancer Center, Houston, TX, USA
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11:20 am – 11:40 am

Ariel E. Marciscano, MD
Weill Cornell Medical College, New York, NY, USA

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11:40 am – 12:00 pm

Panel discussion with
Eric Deutsch, MD, PhD, Alan Melcher MD, PhD and Anna Wilkins, MD, PhD

12:00 pm - 12:15 pm

Concluding remarks

Silvia C. Formenti, MD
Weill Cornell Medical College, New York, NY, USA